Clinicopathologic and prognostic studies on young male with lung adenocarcinoma

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Background and purpose:Adenocarcinoma is the main type of lung cancer and the ages of most patients with adenocarcinoma are over-40 years, the young patients with the disease are rare, and the 5-year survival rate of the young male with lung adenocarcinoma is poor. This study was done to explore the survival and prognosis of young male with lung adenocarcinoma. Methods:A total of 110 surgically treated patients with lung adenocarcinoma were analyzed retrospectively to study the relationship between the prognostic factors and survival. Results:The analysis showed that the overall 5-year survival rate of the young male with lung adenocarcinoma was 34.5%, it was 29.0% for smokers and 42.6% for non-smokers(P0.05). The 5-year survival rates of staging Ⅰ,Ⅱ,Ⅲ and Ⅳ were 68.8%,35.7%, 14.3% and 0, respectively(P0.01),the survival rates of the patients with the number of involved lymph nodes3 compared to ≤3 were 28.5% and 48.1%(P0.01). Conclusion:Smoking, p-TNM, the number of involved lymph nodes was correlated with the survival, effective smoking control efforts and total lymphadenectomy are important to the survival of lung adenocarcinoma among young males.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.