Jiangzhi and Hepatoprotective effect of salidroside on nonalcoholic fatty liver disease

Résumé fourni par la source

Objective:To explore the intervening effect of the main components of the rhodiola on the nonalcoholic fatty liver disease(NAFLD) for male golden hamsters induced by high-fat diets.Methods:Total 18 male golden hamsters were divided into control group,model group and salidroside group randomly.Male golden hamsters in the model group and salidroside group were fed with high fat diet for 6 weeks to reproduce NAFLD model.After the second week of feeding,male golden hamsters in the salidroside group were given a gavage of salidroside.All male golden hamsters were put to death at the 6 weeks and samples were collected.Hepatic tissue TG contents were detected.Serum AST activities were determined.Hepatic tissues were detected by HE staining.Results:Salidroside decreased hepatic tissue TG contents,serum AST activities and reduced the fatty degeneration in hepatocytes significantly.Conclusion:Salidroside has conspicuous pharmacological effect on the nonalcoholic fatty liver disease in male golden hamsters.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.