One-year outcomes of Valiant-Captivia
Rattachement africain : de, gb, it, nl, tr. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Objectives: To evaluate 1-yr mortality, morbidity, and aortic remodeling in the Valiant-Captivia Registry following thoracic endovascular aortic repair (TEVAR). Methods: 100 (81 m; mean age 65 ± 12 yr) eligible pts implanted with the Valiant Captivia System at 15 sites in Europe and Turkey between 10/09 and 6/10 were enrolled. Indications included descending thoracic aortic aneurysm (TAA, 49%), aortic dissection (42%: acute (AD) 19%, chronic (CD) 23%), and 9% other. Results: Technical success was 100%, with no misaligned deployment or aortic perforation. No pts were lost to follow up. The 30-d rate of all-cause mortality (ACM) was 4%. One-yr ACM was 15% and aneurysm-related mortality (ARM) was 11% with no significant difference among TAA, AD, and CD ACM or ARM within 1 yr. Retrograde type A dissection occurred in 2%; rupture in 5% within 1 yr. A conversion to open surgery during intraoperative aneurysm rupture was successful; another conversion at day 59 resulted in death. Nonfatal stroke occurred in 6% (5/6 TAA, 1/6 other) and paraplegia in 1% (TAA). MAEs occurred in 23% within 1 yr. Among 61 pts with 1-yr imaging evaluable for endoleak (EL), 6.6% had type I (1 AD) and 11.5% had type II EL (7/61; 2TAA, 2AD, 3CD). None had types III or IV. One patient with type II EL died before scheduled embolization. Aneurysm growth > 5 mm was found in 13 pts (6TAA, 3AD, 4CD) at 1 yr. One died and 3 required interventions, one for device migration. Freedom from re-intervention at 1 year was 86%. Among all dissection pts, no false lumens were patent at the level of the stent graft: 64% had complete and 36% had partial thrombosis, with evidence of continued perfusion of the false lumen from unstented regions of the aorta, although a paucity of data precluded analysis. 73% of CD and 54% of AD had complete thrombosis (ns). Minimal true lumen diameter increased from 10.1 ± 7.5 mm at baseline to 18.5 ± 9.3 mm at 1 yr in AD (p = 0.02) and from 17.7 ± 11.4 to 23.7 ± 9.6 mm in CD (ns). The false lumen shrank from 43.1 ± 15.0 mm at baseline to 22.5 ± 14.6 mm (p = 0.0004) at 1 yr in CD; this was not evident in AD. Fig. 1 Conclusions: The high technical success and positive clinical outcome rates showed that the Valiant Captivia Thoracic Stent Graft has promising capacity to treat a variety of thoracic aortic conditions. Evidence of remodeling in dissection pts was found at the level of stent graft, with expansion of the true lumen in both AD and CD and degeneration of the false lumen particularly in CD.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- One-year outcomes of Valiant-Captivia
- Date Crossref
- 23/01/2013
- Éditeur
- Georg Thieme Verlag KG
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
-
Medizinische Hochschule Hannover pays non établi dans la noticeUniversité ou école supérieure
-
St George's Hospital pays non établi dans la noticeÉtablissement de santé
-
IRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola pays non établi dans la noticeÉtablissement de santé
-
St. Antonius Ziekenhuis pays non établi dans la noticeOrganisme public
-
Dokuz Eylül University pays non établi dans la noticeUniversité ou école supérieure
-
University Hospital Ulm pays non établi dans la noticeÉtablissement de santé
-
St. George's Hospital pays non établi dans la noticeÉtablissement de santé
-
Policlinico S. Orsola-Malpighi pays non établi dans la noticeÉtablissement de santé
-
St. Antonius Hospital pays non établi dans la noticeÉtablissement de santé
-
Universitätsklinikum pays non établi dans la noticeInstitution
Medizinische Hochschule Hannover, St George's Hospital et IRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola, avec 7 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.