Influence of Patient Age on Angioarchitecture of Brain Arteriovenous Malformations
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Le résumé fourni par la source
BACKGROUND AND PURPOSE: The imaging characteristics and modes of presentation of brain AVMs may vary with patient age. Our aim was to determine whether clinical and angioarchitectural features of brain AVMs differ between children and adults. MATERIALS AND METHODS: A prospectively collected institutional data base of all patients diagnosed with brain AVMs since 2001 was queried. Demographic, clinical, and angioarchitecture information was summarized and analyzed with univariable and multivariable models. RESULTS: Results often differed when age was treated as a continuous variable as opposed to dividing subjects into children (18 years or younger; n = 203) versus adults (older than 18 years; n = 630). Children were more likely to present with AVM hemorrhage than adults (59% versus 41%, P < .001). Although AVMs with a larger nidus presented at younger ages (mean of 26.8 years for >6 cm compared with 37.1 years for <3 cm), this feature was not significantly different between children and adults (P = .069). Exclusively deep venous drainage was more common in younger subjects when age was treated continuously (P = .04) or dichotomized (P < .001). Venous ectasia was more common with increasing age (mean, 39.4 years with ectasia compared with 31.1 years without ectasia) and when adults were compared with children (52% versus 35%, P < .001). Patients with feeding artery aneurysms presented at a later average age (44.1 years) than those without such aneurysms (31.6 years); this observation persisted when comparing children with adults (13% versus 29%, P < .001). CONCLUSIONS: Although children with brain AVMs were more likely to come to clinical attention due to hemorrhage than adults, venous ectasia and feeding artery aneurysms were under-represented in children, suggesting that these particular high-risk features take time to develop.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Influence of Patient Age on Angioarchitecture of Brain Arteriovenous Malformations
- Date Crossref
- 13/03/2014
- Éditeur
- American Society of Neuroradiology (ASNR)
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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University of California H.F.) pays non établi dans la noticeUniversité ou école supérieure
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Child Neurology Associates pays non établi dans la noticeÉtablissement de santé
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Neurological Surgery pays non établi dans la noticeÉtablissement de santé
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From the Division of Neurointerventional Radiology (S.W.H. pays non établi dans la noticeInstitution
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Center for Cerebrovascular Research (J.N. pays non établi dans la noticeInstitution
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cDivision of Pediatric Neurosurgery (N.G.) pays non établi dans la noticeInstitution
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eDivision of Child Neurology (H.F.) pays non établi dans la noticeInstitution
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Division of Cerebrovascular Neurosurgery (M.T.L.) pays non établi dans la noticeInstitution
H.F.) — University of California, Child Neurology Associates et Neurological Surgery, avec 5 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.