Cultured epithelial allografting of leg ulcers
Rattachement africain : gb. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Fifty-two venous ulcers, with a mean duration of 12 years, were treated with cultured epithelial allografts. 43% of ulcers were completely healed between 7 and 28 days after the procedure, with the remaining lesions reduced by 45% of their original area. Identification of the cells of origin in a culture-grafted ulcer remains elusive. Clinically there was no convincing evidence of graft ‘take’, healing clearly progressing inwards from the ulcer edge. It seems likely that this healing reflects a biological effect rather than graft survival. Despite being unable to provide evidence of incorporation of donor cells, the beneficial effect of the epithelial allografts is clear, two-thirds of these ulcers had a ‘control’ period of conventional treatment with only minimal healing occurring. The patients in this study were treated as inpatients but the procedure could easily be carried out in the outpatient dept.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Cultured epithelial allografting of leg ulcers
- Date Crossref
- 01/01/1989
- Éditeur
- Informa UK Limited
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Les institutions déclarées
Une affiliation ne permet pas de déduire la nationalité d’un auteur.