Symptom profile in obese asthmatics compared with non obese asthmatics in stable state

Le résumé fourni par la source

It has been proposed that in asthmatic subjects with obesity (O) it is more difficult to achieve symptom control when compared with non obese patients (NO). The aim of this study was to establish a symptom profile in outpatient asthmatics, comparing O with NO subjects. We included patients with confirmed Asthma, who had filled prescriptions for at least 1 year. They should not have other respiratory illness or systemic uncontrolled disease. Subjects answered the Asthma Control Questionnaire (ACT), and clinical charts were reviewed for demographic, medical and therapeutic information. ACT scores from 5 (worst control) to 25 (total control). Obesity was defined as BMI ≥30 Kg/m2. Statistical analysis was done with t test and chi2. Results are presented as mean±SD. 223 patients were included (93 O, 130 NO), with FEV1 77±21%, and asthma for 21.5±14.2 years. O group was older (55.6±15.6 vs 48.2±20.8 years old; p=0.004), had more women (85 vs 64%, p=0.001), less atopy (71 vs 84%, p 2 controller drugs in 19 vs 7% (p In this group of asthmatic patients we found that O subjects had worse control than NO, with a different symptom profile, despite receiving more treatment.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.