Prevalence of Asymptomatic Cerebral Aneurysm in General population and Ischemic Stroke Patient (S47.007)

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Background and Objective: The reported prevalence of asymptomatic cerebral aneurysm (CA) in the general population is 0.5-3[percnt] in imaging studies. However the frequency of aneurysm in ischemic stroke patients has not been investigated. The purpose of this study was to assess the prevalence of CA in ischemic stroke patient compared to the general population and find the factors related with CA in ischemic stroke patients. Methods: We retrospectively reviewed 695 ischemic stroke patients who admitted between 2011 and 2013, and 2118 controls from the general population who were evaluated for routine health care at the same hospital between 2011 and 2012. All patients underwent MR imaging and MR angiography. Stroke subtype was decided by the Trial of Org 10172 in Acute Stroke Treatment (TOAST) classification. Results: CAs were found in 80 persons from the general population (3.8[percnt]; 36 men and 44 women; age 37 to 76 years, mean 57) and in 52 ischemic stroke patients (7.5[percnt]; 26 men and 26 women; age 43 to 91 years, mean 66). A comparison of the prevalence of CA showed an increased prevalence in patients with ischemic stroke compared with the general population (OR 2.06, 95[percnt] CI 1.437-2.954, p<0.001), and when categorized according to age by decade, the 7th decade was significantly different (p<0.001). Multivariate analysis showed that only hypertension (p = 0.04) correlated with the increased prevalence of CA in ischemic stroke patients. Age, sex, diabetes, hyperlipidemia, previous stroke, smoking, and family history of cerebrovascular accident were not associated CA. Also there was no relationship between the stroke subtype and presence of CA. Conclusions: CA was more common in ischemic stroke patients than general population, especially in the 7th decade. Among the various vascular risk factors, hypertension was only correlated with increased prevalence of CA in ischemic stroke patients.

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