Eastern Equine Encephalitis in Latin America
Rattachement africain : pa, us, Burkina Faso, ru, pl. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
BACKGROUND: The eastern equine encephalitis (EEE) and Venezuelan equine encephalitis (VEE) viruses are pathogens that infect humans and horses in the Americas. Outbreaks of neurologic disease in humans and horses were reported in Panama from May through early August 2010. METHODS: We performed antibody assays and tests to detect viral RNA and isolate the viruses in serum samples from hospitalized patients. Additional cases were identified with enhanced surveillance. RESULTS: A total of 19 patients were hospitalized for encephalitis. Among them, 7 had confirmed EEE, 3 had VEE, and 1 was infected with both viruses; 3 patients died, 1 of whom had confirmed VEE. The clinical findings for patients with EEE included brain lesions, seizures that evolved to status epilepticus, and neurologic sequelae. An additional 99 suspected or probable cases of alphavirus infection were detected during active surveillance. In total, 13 cases were confirmed as EEE, along with 11 cases of VEE and 1 case of dual infection. A total of 50 cases in horses were confirmed as EEE and 8 as VEE; mixed etiologic factors were associated with 11 cases in horses. Phylogenetic analyses of isolates from 2 cases of equine infection with the EEE virus and 1 case of human infection with the VEE virus indicated that the viruses were of enzootic lineages previously identified in Panama rather than new introductions. CONCLUSIONS: Cases of EEE in humans in Latin America may be the result of ecologic changes that increased human contact with enzootic transmission cycles, genetic changes in EEE viral strains that resulted in increased human virulence, or an altered host range. (Funded by the National Institutes of Health and the Secretaría Nacional de Ciencia, Tecnología e Innovación, Panama.).
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Eastern Equine Encephalitis in Latin America
- Date Crossref
- 22/08/2013
- Éditeur
- Massachusetts Medical Society
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Universidad de Panamá pays non établi dans la noticeUniversité ou école supérieure
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Instituto Conmemorativo Gorgas de Estudios de la Salud pays non établi dans la noticeStructure de recherche
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University of Pennsylvania Department of Medicine pays non établi dans la noticeUniversité ou école supérieure
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Hospital del Niño pays non établi dans la noticeÉtablissement de santé
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Direction Générale de la Météorologie Burkina Faso (code pays fourni par la source)Institution
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Ministry of Health of the Russian Federation Department of Epidemiology pays non établi dans la noticeOrganisme public
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Ministry of Agriculture and Rural Development pays non établi dans la noticeOrganisme public
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Gorgas Memorial Institute of Health Studies Department of Research in Virology and Biotechnology pays non établi dans la noticeStructure de recherche
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Department of Research in Virology and Biotechnology pays non établi dans la noticeInstitution
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University of Panama Gorgas Memorial Institute of Health Studies pays non établi dans la noticeUniversité ou école supérieure
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University of Texas Medical Branch Institute for Human Infections and Immunity pays non établi dans la noticeUniversité ou école supérieure
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General Direction pays non établi dans la noticeInstitution
Universidad de Panamá, Instituto Conmemorativo Gorgas de Estudios de la Salud et Department of Medicine — University of Pennsylvania, avec 9 autres affiliations. Pays d’affiliation : Burkina Faso.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.