A prospective cohort study to investigate cost-minimisation, of Traditional open, open fAst track recovery and laParoscopic fASt track multimodal management, for surgical patients with colon carcinomas (TAPAS study)
Rattachement africain : cw, nl. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
BACKGROUND: The present developments in colon surgery are characterized by two innovations: the introduction of the laparoscopic operation technique and fast recovery programs such as the Enhanced Recovery After Surgery (ERAS) recovery program. The Tapas-study was conceived to determine which of the three treatment programs: open conventional surgery, open 'ERAS' surgery or laparoscopic 'ERAS' surgery for patients with colon carcinomas is most cost minimizing? METHOD/DESIGN: The Tapas-study is a three-arm multicenter prospective cohort study. All patients with colon carcinoma, eligible for surgical treatment within the study period in four general teaching hospitals and one university hospital will be included. This design produces three cohorts: Conventional open surgery is the control exposure (cohort 1). Open surgery with ERAS recovery (cohort 2) and laparoscopic surgery with ERAS recovery (cohort 3) are the alternative exposures. Three separate time periods are used in order to prevent attrition bias. Primary outcome parameters are the two main cost factors: direct medical costs (real cost price calculation) and the indirect non medical costs (friction method). Secondary outcome parameters are mortality, complications, surgical-oncological resection margins, hospital stay, readmission rates, time back to work/recovery, health status and quality of life. Based on an estimated difference in direct medical costs (highest cost factor) of 38% between open and laparoscopic surgery (alfa = 0.01, beta = 0.05), a group size of 3 x 40 = 120 patients is calculated. DISCUSSION: The Tapas-study is three-arm multicenter cohort study that will provide a cost evaluation of three treatment programs for patients with colon carcinoma, which may serve as a guideline for choice of treatment and investment strategies in hospitals. TRIAL REGISTRATION: ISRCTN44649165.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- A prospective cohort study to investigate cost-minimisation, of Traditional open, open fAst track recovery and laParoscopic fASt track multimodal management, for surgical patients with colon carcinomas (TAPAS study)
- Date Crossref
- 14/06/2010
- Éditeur
- Springer Science and Business Media LLC
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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St. Elisabeth Hospital pays non établi dans la noticeÉtablissement de santé
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Curaçao Medical Center pays non établi dans la noticeÉtablissement de santé
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Radboud University Nijmegen pays non établi dans la noticeUniversité ou école supérieure
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Radboud University Medical Center pays non établi dans la noticeOrganisme public
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University Medical Center Utrecht pays non établi dans la noticeÉtablissement de santé
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Elisabeth-TweeSteden Ziekenhuis pays non établi dans la noticeÉtablissement de santé
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Ziekenhuis Gelderse Vallei pays non établi dans la noticeÉtablissement de santé
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Canisius-Wilhelmina Ziekenhuis pays non établi dans la noticeÉtablissement de santé
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Maastricht University Medical Centre pays non établi dans la noticeOrganisme public
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Sint Elisabeth Hospital Department of Surgery pays non établi dans la noticeÉtablissement de santé
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Department of Surgery pays non établi dans la noticeInstitution
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Department of Epidemiology and Statistics pays non établi dans la noticeInstitution
St. Elisabeth Hospital, Curaçao Medical Center et Radboud University Nijmegen, avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.