Cigarette smoking and risk of death from colorectal cancer in women
Rattachement africain : us, ca, ch, de. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
OBJECTIVE: Much of the epidemiological evidence concerning the relationship between cigarette smoking and colorectal cancer has come from studies in men, and less is known about the role of smoking in the aetiology and pathogenesis of colorectal cancer in women. Therefore, the purpose of the present study was to investigate the association between cigarette smoking and risk of death from colorectal cancer in a large cohort of women. SUBJECTS AND METHODS: The study was conducted within the cohort of 56 837 women who were enrolled in the Canadian National Breast Screening Study (NBSS) and who completed self-administered dietary questionnaires. (The NBSS is a randomized controlled trial of screening for breast cancer in women aged 40-59.) During follow up to December 31, 1993, 90 women died from colorectal cancer (79 from colon cancer, 11 from rectal cancer). Deaths were ascertained by means of record linkage to the Canadian Mortality Database. Cox proportional hazards models were used to estimate hazards ratios (HR) and 95% confidence intervals (CI) for the association between cigarette smoking and risk of death from colorectal cancer, after adjustment for age alone, or age, energy intake, alcohol consumption, and other potentially relevant confounders. RESULTS: Cigarette smoking was not associated with altered risk of death from colorectal cancer. The multivariate HR (95% CI) for the risk in ever smokers compared with that in never smokers was 1.37 (0.86-2.18). There was no evidence for trends in risk with cigarette-years of consumption, and by amount and duration of consumption. CONCLUSION: The results of this study suggest that cigarette smoking is not associated with altered risk of death from colorectal cancer in women. However, given the possibility that the association between cigarette smoking and colorectal cancer might not become evident until at least 30-40 years after the commencement of smoking, it might still be too early to detect an association, since uptake of smoking by women occurred later than uptake by men.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Cigarette smoking and risk of death from colorectal cancer in women
- Date Crossref
- 01/09/2000
- Éditeur
- Wiley
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
-
Albert Einstein College of Medicine Department of Epidemiology and Social Medicine pays non établi dans la noticeUniversité ou école supérieure
-
Centre for Addiction and Mental Health pays non établi dans la noticeÉtablissement de santé
-
University of Toronto Department of Public Health Sciences pays non établi dans la noticeUniversité ou école supérieure
-
Toronto Public Health pays non établi dans la noticeOrganisme public
-
World Health Organization pays non établi dans la noticeOrganisme public
-
HAW Hamburg pays non établi dans la noticeUniversité ou école supérieure
-
Ontario Tobacco Research Unit pays non établi dans la noticeStructure de recherche
-
Institute for Clinical Evaluative Sciences pays non établi dans la noticeOrganisation à but non lucratif
-
German Cancer Research Center pays non établi dans la noticeStructure de recherche
-
DKFZ-ZMBH Alliance pays non établi dans la noticeStructure de recherche
-
Addiction Research Foundation Division pays non établi dans la noticeOrganisation à but non lucratif
-
University of Applied Sciences Public Health Sciences pays non établi dans la noticeUniversité ou école supérieure
Department of Epidemiology and Social Medicine — Albert Einstein College of Medicine, Centre for Addiction and Mental Health et Department of Public Health Sciences — University of Toronto, avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.