EXERCISE INDUCED INSULIN, C-PEPTIDE, AND GLUCOSE RESPONSES IN NON-OBESE BLACK AND WHITE FEMALES

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999 The purpose of this study was to compare insulin, C-peptide, and glucose responses of black (n = 7) and white (n = 10) females during 45 min of treadmill exercise. Black females averaged 25.8 yrs old and 25.3% body fat. White females were 26.9 yrs old and 26.8% body fat. T-tests revealed no significant biometric differences (p>.05) between groups. ˙VO2 and RER were determined by indirect calorimetry. Venous blood specimens were drawn after 30 min of rest and at exercise min 15, 30, and 45 from an indwelling cannula. Insulin and C-peptide were determined by radioimmunoassay.˙VO2max for the black females (30.7±4 ml/kg/min) was significantly lower than for white females (36.1±3.5 ml/kg/min). Data for RER, glucose, insulin, and C-peptide were analyzed using ANCOVA with˙VO2max as a covariant. No significant group differences were observed for RER, insulin and C-peptide. A significant covariant effect of˙VO2max (F=6.09, p=.03) and significant group effect (F=5.93, p=.03) were observed for blood glucose levels. Controlling for the effect of˙VO2max, corrected glucose values were 93.7 ± 3.4 mg/dl vs 106 ± 2.9 mg/dl for black and white females, respectively. The black and white females of this study displayed similar patterns of substrate oxidation and hormonal response throughout exercise. The results fail to support previously reported differences between black and white females.

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