Effect of Immunoglobulin Substitution during Plasmapheresis on Serum Immunoglobulin and Complement Concentrations

Le résumé fourni par la source

Plasma exchange is being used increasingly as a ther apeutic intervention in various immune-mediated disor ders [1].The method is hampered, however, not only by numerous difficulties in assessing its efficacy [2], but also by technical problems, such as the depletion of serumproteins [3], When human albumen is used as plasma substituent, the patient receives only this plasma compo nent back, while serum immunoglobulins, complement components, coagulation factors etc. remain reduced.Although infection occurs rather seldom in patients on plasmapheresis (PP), it can constitute a major threat in ' Supported in part by the Anton Dreher Memorial Donation for Medical Research.

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