Myomas, Pregnancy Outcome, and In Vitro Fertilization
Rattachement africain : it, ch. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Uterine fibroids have been reported in 27% of infertile women, and 50% of women with unexplained infertility become pregnant after myomectomy. The age at which a first pregnancy occurs is increasing from the thirties to the forties. This increase and the recurrence rate of leiomyomas from 15 to 30% points to the effect of myomas on the infertility. Mechanisms by which myomas may cause infertility are abnormal uterine contractility, elongation of the uterine cavity, and distortion of uterine vascularization. Surgery may have beneficial or adverse effects without clear data on its effect on the assisted reproductive technology (ART) procedures. The present study was undertaken to establish the impact of surgical removal of myomas on fertility and infertility of patients undergoing ART procedures. Patients who underwent surgical removal of myomas before in vitro fertilization (Group A) had a cumulative success rate of 33% for one to three procedures (28 clinical pregnancies in 84 patients) and delivery rate of 25% (21 live births in 84 patients). Patients who underwent in vitro fertilization without previous surgery (Group B) had a 15% clinical pregnancy rate (13 pregnancies in 84 patients) (P < 0.05) and 12% delivery rate (10 deliveries in 84 pregnancies) (P < 0.05). Abortion rates were 7% (8 deliveries in 84 patients) and 4% (3 deliveries in 84 patients) in Groups A and B, respectively. This study confirms the beneficial effect of surgical removal of fibroids before undergoing ART procedures.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé, mais le titre doit être comparé manuellement.
- Titre Crossref
- Myomas, Pregnancy Outcome, and <i>In Vitro</i> Fertilization
- Date Crossref
- 01/12/2004
- Éditeur
- Wiley
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Ospedale Infermi di Rimini pays non établi dans la noticeÉtablissement de santé
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University of Bologna Institute of Obstetrics and Gynecology pays non établi dans la noticeUniversité ou école supérieure
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University Hospital of Geneva Department of Obstetrics and Gynecology pays non établi dans la noticeÉtablissement de santé
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Humanitas University pays non établi dans la noticeUniversité ou école supérieure
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University of Bari Aldo Moro Department of Obstetrics and Gynecology pays non établi dans la noticeUniversité ou école supérieure
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Humanitas Clinical Institute Operative Unit of Reproductive Medicine pays non établi dans la noticeStructure de recherche
Ospedale Infermi di Rimini, Institute of Obstetrics and Gynecology — University of Bologna et Department of Obstetrics and Gynecology — University Hospital of Geneva, avec 3 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.