Satisfaction and Side Effects in Outpatients with Schizophrenia Medicated with Antipsychotics

Le résumé fourni par la source

Objective: The aim of the present study was to investigate hidden distress originating from the expected pharmacological features in clinical practice using questionnaires, one of the best methods to communicate distress without the difficulties of verbal communication.Patients: We studied 57 Japanese outpatients with schizophrenia, including 21 taking only first-generation antipsychotics, 20 taking only sedative second-generation antipsychotics, 5 taking only non-sedative second-generation antipsychotics and 11 taking both types of antipsychotics.Methods: The questionnaire comprised from the Treatment Satisfaction Questionnaire for Medication version 1.4 (TSQM). The side effects scale from TSQM was further investigated with the Side Effect Questionnaire.Results: Regarding satisfaction, effectiveness were significantly higher in patients medicated with first-generation antipsychotics than in those medicated with both generations of antipsychotics. Convenience were significantly lower in patients medicated with both generations of antipsychotics than in those medicated with first-generation or sedative second-generation antipsychotics. No significant difference among the groups was found regarding side effects.Conclusions: For outpatients voluntarily receiving pharmacotherapy, side effects were not the main dissatisfaction factor because these were controlled to a certain extent in practical treatment. For these patients, convenience and effectiveness were the most important factors for their satisfaction.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.