Prevalence of Chronic Kidney Disease in Patients with Spinal Cord Injuries/Disorders
Rattachement africain : us, vn. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
BACKGROUND AND OBJECTIVES: Chronic kidney disease (CKD) and spinal cord injury and disorders (SCI/D) are common and costly conditions among Veterans. However, little is known about CKD among adults with SCI/D. METHODS: We conducted cross-sectional analyses of Veterans with SCI/D across all VA facilities in 2006. CKD was defined as an estimated glomerular filtration rate (eGFR) <60 ml/min/1.73 m(2) and categorized by standard eGFR strata. eGFR was calculated in two ways: (a) the Modification of Diet in Renal Disease (MDRD) equation and (b) the MDRD equation + an empirically derived correction factor for SCI/D (MDRD-SCI/D). Logistic regression models were used to examine the relationship between patient characteristics and CKD. RESULTS: Among 9,333 SCI/D Veterans with an available eGFR, the proportion with CKD was substantially higher based on the MDRD-SCI/D equation (35.2%) than based on the MDRD equation (10.2%). In adjusted analyses, while older age (OR for >65 years = 2.53; 95% CI: 2.21-2.89), female sex (OR 2.18; 95% CI: 1.62-2.92), and a non-traumatic cause for injury (OR 1.39; 95% CI: 1.23-1.57) were associated with an increased odds of CKD, black race (OR 0.64; 95% CI: 0.56-0.72) and a duration of injury of ≥10 years (OR 0.76; 95% CI: 0.67-0.86) were associated with a decreased odds of CKD. Diagnostic codes for CKD and nephrology visits were infrequent for SCI/D Veterans with CKD (27.51 and 6.58%, respectively). CONCLUSION: Using a recently validated version of the MDRD equation with a correction factor for SCI/D, over 1 in 3 Veterans with SCI/D had CKD, which is more than 3-fold higher than when traditional MDRD estimation is used.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Prevalence of Chronic Kidney Disease in Patients with Spinal Cord Injuries/Disorders
- Date Crossref
- 01/01/2012
- Éditeur
- S. Karger AG
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Jr. VA Hospital Edward Hines pays non établi dans la noticeÉtablissement de santé
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University of Illinois Hospital & Health Sciences System pays non établi dans la noticeÉtablissement de santé
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Jesse Brown VA Medical Center Medicine Service pays non établi dans la noticeÉtablissement de santé
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Loyola University Chicago pays non établi dans la noticeUniversité ou école supérieure
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General Department of Preventive Medicine pays non établi dans la noticeOrganisme public
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Quality Enhancement Research Initiative pays non établi dans la noticeInstitution
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Northwestern University Institute for Healthcare Studies pays non établi dans la noticeUniversité ou école supérieure
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Health Research and Educational Trust pays non établi dans la noticeOrganisation à but non lucratif
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Center for Management of Complex Chronic Care pays non établi dans la noticeInstitution
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University of Illinois Hospital and Health Sciences System Department of Medicine pays non établi dans la noticeUniversité ou école supérieure
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Loyola University Stritch School of Medicine Department of Medicine pays non établi dans la noticeUniversité ou école supérieure
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General Medicine pays non établi dans la noticeInstitution
Edward Hines — Jr. VA Hospital, University of Illinois Hospital & Health Sciences System et Medicine Service — Jesse Brown VA Medical Center, avec 9 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.