Treatment of prosthetic joint infections due toPropionibacterium
Rattachement africain : nl, us. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
BACKGROUND AND PURPOSE: Currently, Propionibacterium is frequently recognized as a causative microorganism of prosthetic joint infection (PJI). We assessed treatment success at 1- and 2-year follow-up after treatment of Propionibacterium-associated PJI of the shoulder, hip, and knee. Furthermore, we attempted to determine whether postoperative treatment with rifampicin is favorable. PATIENTS AND METHODS: We conducted a retrospective cohort study in which we included patients with a primary or revision joint arthroplasty of the shoulder, hip, or knee who were diagnosed with a Propionibacterium-associated PJI between November 2008 and February 2013 and who had been followed up for at least 1 year. RESULTS: We identified 60 patients with a Propionibacterium-associated PJI with a median duration of 21 (0.1-49) months until the occurrence of treatment failure. 39 patients received rifampicin combination therapy, with a success rate of 93% (95% CI: 83-97) after 1 year and 86% (CI: 71-93) after 2 years. The success rate was similar in patients who were treated with rifampicin and those who were not. INTERPRETATION: Propionibacterium-associated PJI treated with surgery in combination with long-term antibiotic administration had a successful outcome at 1- and 2-year follow-up irrespective of whether the patient was treated with rifampicin. Prospective studies are needed to determine whether the use of rifampicin is beneficial in the treatment of Propionibacterium-associated PJI.
Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.
Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé, mais le titre doit être comparé manuellement.
- Titre Crossref
- Treatment of prosthetic joint infections due to<i>Propionibacterium</i>
- Date Crossref
- 28/09/2015
- Éditeur
- Informa UK Limited
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
-
Sint Maartenskliniek pays non établi dans la noticeÉtablissement de santé
-
Radboud University Nijmegen pays non établi dans la noticeUniversité ou école supérieure
-
University Medical Center d Department of Medical Microbiology pays non établi dans la noticeÉtablissement de santé
-
Radboud University Medical Center pays non établi dans la noticeOrganisme public
-
Canisius-Wilhelmina Ziekenhuis pays non établi dans la noticeÉtablissement de santé
-
a Department of Orthopaedic Surgery pays non établi dans la noticeInstitution
-
b Department of Research pays non établi dans la noticeInstitution
-
c Department of Medical Microbiology and Infectious Diseases pays non établi dans la noticeInstitution
Sint Maartenskliniek, Radboud University Nijmegen et d Department of Medical Microbiology — University Medical Center, avec 5 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.