University Hospitals Geauga Medical Center

Case report: rare progressive cavitary lesion in progressive multifocal leukoencephalopathy

Mindy Hoang, Richard HC Lai

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C50-18 HSV-Triggered Hemophagocytic Lymphohistiocytosis (HLH) With Persistent Encephalopathy in an Immunocompetent Elderly ICU Patient

S M Noureldin, L Sankari, L Al Bizri, A Shuster

Abstract Case Presentation An 81-year-old immunocompetent man with hyperlipidemia and hypothyroidism presented after a fall, reporting several days of progressive fatigue and low-grade fever. Laboratory evaluation revealed pancytopenia, marked transaminitis, and elevated inflammatory markers. He rapidly decompensated, necessitating ICU transfer for worsening …

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A50-11 More Than Just Low Sodium: Unmasking Neuroborreliosis Behind Hyponatremia

A Chubinidze, O Kaiwan, K Chen, A A Halawa et autres

Abstract Introduction Lyme disease, caused by the spirochete Borrelia burgdorferi, is a tick-borne infection with multisystem involvement, commonly affecting the skin, joints, heart, and nervous system. Neuroborreliosis, though less frequent, may manifest with meningitis, cranial neuropathies, or radiculopathies. Older adults can present …

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A49-26 Not Your Usual Pseudomonas: A Rare Case of Pseudomonas Stutzeri Bacteremia With Community-Onset Presentation

O Kaiwan, A Houry, A Sidley, C Peng

Abstract Introduction Pseudomonas stutzeri is a non-fluorescent, oxidase-positive, gram-negative bacillus commonly found in soil and water. Unlike Pseudomonas aeruginosa, it is regarded as a low-virulence organism and uncommonly associated with human infection. Reported cases have been linked to healthcare exposure, prosthetic devices, …

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B49-26 Candida Lusitaniae as a Rare Etiology of Infective Endocarditis: A Case Report

A Houry, O Kaiwan, S Willis, C Peng

Abstract Introduction Candida species are commonly a part of the normal human microbiota, inhabiting non-sterile tissues such as the respiratory, gastrointestinal, urinary, and genital tracts, as well as the skin, fingernails, and oral cavity. Candida species represent the leading etiological agents of …

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Comparative Efficacy and Safety of Glucagon Receptor Agonists on Metabolic Outcomes: A Network Meta‐Analysis of Randomised Controlled Trials

Ayah Abulehia, Hazem Ayesh, Omar Ayesh, Doha Jaber et autres

ABSTRACT Introduction Glucagon receptor agonists (GRAs) are an emerging class of therapies for obesity and type 2 diabetes, demonstrating encouraging metabolic and weight‐reducing effects. Several investigational GRA‐based agents, including retatrutide, cotadutide, mazdutide, and survodutide, have reported promising results across early and mid‐phase …

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Abstract 4368674: Tension in the Air - Cardiac Tamponade Secondary to Tension Pneumomediastinum

Shamin Mahmud, Sanjana Datla, Minh Trang Hoang, Zachary Chroust et autres

Intro: Cardiac tamponade is a common cause of obstructive shock, often necessitating urgent intervention. We delineate a rare case of cardiac tamponade and shock due to tension pneumomediastinum (TP). Case Presentation: A 53-year-old man with metastatic paranasal squamous cell carcinoma (SCC) was …

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Nanoencapsulated Sirolimus Plus Pegadricase (NASP) Reduces Gout Clinical Manifestations in Patients with Uncontrolled Gout (UG) and Stage 3 CKD

Nissreen Elfadawy, Puja P. Khanna, Rehan Azeem, Ben Peace et autres

Background: Patients (pts) with UG often have chronic kidney disease (CKD). CKD limits urate-lowering therapy efficacy in UG, amplifying the unmet needs for pts with CKD. NASP (formerly SEL-212) is an investigational, novel, every 4-wk (Q4W), sequential 2-component infusion therapy consisting of …

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Therapy-Related-Myeloid-Neoplasm-Risk Score: a convenient score for therapy-related myeloid neoplasms risk assessment in adult cancer patients

Abhay Singh, Megan M. Herr, Rusina Karia, Theresa Hahn et autres

BACKGROUND: A prediction model for estimating risk of therapy-related myeloid neoplasms (tMNs), a late effect with a high mortality after chemotherapy and/or radiation, is currently unavailable. Ability to predict risk at initial cancer presentation can be key for early detection and risk …

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In Reply to Devlin et al

Erin McClure, Mairead Moloney, Yuxuan Jin, Liang Yu

Thank you for reading our article and sharing your concerns. Overall, while we appreciate you taking the time to discuss our work, we were surprised to find the majority of the comments to be anecdotal, written in somewhat inflammatory language, or related …

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Socio‐Epidemiological Correlates of Anemia Among Non‐Pregnant Females of East and West Uttar Pradesh, India: A NFHS‐5 Secondary Data Analysis Highlighting the Need for Precision Public Policy

Sonam Maheshwari, Richa Sinha, Neil S Patel, Okashah Kaiwan et autres

ABSTRACT Anemia remains a persistent public health challenge in India, disproportionately affecting women and undermining maternal and reproductive health outcomes. Despite nationwide efforts, the burden of anemia continues to vary widely across regions, reflecting complex socio‐demographic determinants. This study aims to identify …

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Ultimate frisbee related injury patterns: A decade long institutional experience

Matthew Coulter, Jayesh Gupta, Shaun Johnson, Nathan Amann et autres

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