Eternity Bioscience (United States)

Test Submission For Notifications # 03

Jhoan Munoz

us (code pays fourni par la source)

eDNAqua-Plan Deliverable 16: Roadmap for implementation of the optimal system(s) /workflow(s)

Tim Collart, Carlijn Adriënne Koole, Oonagh McMeel, Katrina M. Exter et autres

This Roadmap summarises significant outputs generated throughout the three-year eDNAqua-Plan project. These outputs, particularly the eDNAqua-Plan Blueprint, contain the detail and justification that guided the development of this Roadmap. Readers are advised to refer to the relevant documents for details, all of …

Afrique du Sud, be, fr, gb, de, fi, us (code pays fourni par la source)

eDNAqua-Plan Deliverable 16: Roadmap for implementation of the optimal system(s) /workflow(s)

Tim Collart, Carlijn Adriënne Koole, Oonagh McMeel, Katrina M. Exter et autres

This Roadmap summarises significant outputs generated throughout the three-year eDNAqua-Plan project. These outputs, particularly the eDNAqua-Plan Blueprint, contain the detail and justification that guided the development of this Roadmap. Readers are advised to refer to the relevant documents for details, all of …

Afrique du Sud, be, fr, gb, de, fi, us (code pays fourni par la source)

eDNAqua-Plan Deliverable 14: Blueprint for future systems/workflow(s)

Katrina M. Exter, Emilie Boulanger, Paolo Tagliolato, Stephen K. Formel et autres

The eDNAqua-Plan Blueprint presents a comprehensive vision for a future FAIR – and in particular interoperable, machine-actionable – digital ecosystem for environmental DNA (eDNA) and its omics and biodiversity data and metadata. The report synthesises outputs from the previous eDNAqua-Plan work package …

be, fr, it, us, fi, de, il, es, gb (code pays fourni par la source)

Test Submission For Notifications # 02

Jhoan Munoz

us (code pays fourni par la source)

AI-driven identification of a novel small-molecule modulator targeting SNX10 to inhibit osteoclastic bone resorption

Yihe Li, Qihang Wu, Shengnan Qin, Ruth Seeber et autres

Current antiresorptive therapies reduce bone loss by eliminating osteoclasts or inhibiting their formation. However, these approaches could disrupt osteoclast-osteoblast communication and cause serious complications with long-term usage. There is a need for developing new therapies that selectively inhibit resorptive function, while preserving …

au, cn, us, gb (code pays fourni par la source)

eDNAqua-Plan Deliverable 14: Blueprint for future systems/workflow(s)

Katrina M. Exter, Emilie Boulanger, Paolo Tagliolato, Stephen K. Formel et autres

The eDNAqua-Plan Blueprint presents a comprehensive vision for a future FAIR – and in particular interoperable, machine-actionable – digital ecosystem for environmental DNA (eDNA) and its omics and biodiversity data and metadata. The report synthesises outputs from the previous eDNAqua-Plan work package …

be, fr, it, us, fi, de, il, es, gb (code pays fourni par la source)

1514-P: Real-World Barriers Contributing to Clinical Inertia in Type 2 Diabetes: A Pharmacist-Focused Educational Outcomes Study

DIANA ISAACS, FARAH (ROSE) BUSZKA, BRIANNA WINTERS, MEAGAN BRIXIE

Introduction and Objective: The growing prevalence of diabetes requires responsive management. The objectives of this study were to characterize real-world barriers contributing to inertia in T2D among pharmacists and to evaluate changes in confidence and competence following a CE program. Methods: Local …

us (code pays fourni par la source)

Development of a translational murine model for antibody-drug conjugate-induced interstitial lung disease

Suresh Anaganti, Arti Bhujade, Steven Murkli, Zachary Sparta et autres

, is transforming HER2+ breast cancer treatment but is linked to severe off-target toxicity, notably interstitial lung disease (ILD), a serious and mechanistically unresolved adverse event. The preclinical prediction of ILD, however, remains poor and largely dependent on non-human primates (NHP). Here, …

us (code pays fourni par la source)

Test Submission For Notifications 01

Jhoan Manuel Munoz Serrano

us (code pays fourni par la source)

Bulk RNA sequencing of human post-mortem brain tissue from Parkinson's disease and control donors

Christina E. Toomey, Aine Fairbrother-Browne, Jonathan Brenton, Melissa Grant‐Peters et autres

This Zenodo deposit contains a publicly available description of the Dataset: Title: "Bulk RNA sequencing of human post-mortem brain tissue from Parkinson's disease and control donors". Description: Bulk RNA-seq data from 234 samples derived from PMDBS samples across Substantia Nigra, Caudate, Putamen, …

gb, us, it, pk (code pays fourni par la source)

Autologous Ex Vivo Lentiviral Gene Therapy for Pediatric Patients with Severe Leukocyte Adhesion Deficiency-I Provides Sustained Efficacy with a Favorable Safety Profile

Claire Booth, Julián Sevilla, Elena Almarza, Caroline Y. Kuo et autres

Background Severe leukocyte adhesion deficiency-I (LAD-I) results from biallelic deleterious ITGB2 variants leading to deficient/defective CD18 leukocyte expression and impaired endothelial adhesion and extravasation. Children with <2% of normal CD18 neutrophil expression experience recurrent, life-threatening bacterial and fungal infections, and extensive mortality. …

gb, es, us, de (code pays fourni par la source)