Accès ouvert
2026
article
OpenAlex
Lucian Beer, Hannes Kühtreiber, Lisa Auer, Tanja Wagner et autres
Epidermal keratinocytes (KCs) undergo a tightly orchestrated differentiation programme that culminates in the formation of a protective barrier between the body and the environment. Although this process has been studied extensively, several regulators that coordinate KC survival, stratification, and terminal differentiation remain …
at, de
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Accès ouvert
2026
article
OpenAlex
Tania Crombet Ramos, Arlhee Díaz Miqueli, Rolando Pérez Rodríguez
Nimotuzumab is a humanized anti-EGFR monoclonal antibody with a unique pharmacodynamic profile characterized by intermediate affinity and bivalent binding dependence, enabling density-selective tumor targeting while sparing normal tissues from the severe skin rash and other toxicities common to EGFR inhibitors. Since its …
cu, de
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Accès ouvert
2026
dataset
OpenAlex
Barbara Bulgarelli, Davide D’Alimonte, Giuseppe Zibordi, Tamito Kajiyama
Spectral correction factors for the removal of glint perturbations in above-water radiometric measurements are theoretically computed for representative inland, coastal and open-ocean waters, accounting for spectral and atmospheric dependences. The simulation framework relies on the measurement protocol adopted by AERONET-OC, and endorsed …
be, us, de
(code pays fourni par la source)
Accès ouvert
2026
dataset
OpenAlex
Barbara Bulgarelli, Davide D’Alimonte, Giuseppe Zibordi, Tamito Kajiyama
Spectral correction factors for the removal of glint perturbations in above-water radiometric measurements are theoretically computed for representative inland, coastal and open-ocean waters, accounting for spectral and atmospheric dependences. The simulation framework relies on the measurement protocol adopted by AERONET-OC, and endorsed …
be, us, de
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Claudia Fierro, Sara Giovannini, Valeria Moriconi, Claudia Fiorilli et autres
/JARID1B as a candidate target. Of note, JARID1B is indispensable for efficient recruitment of several DNA damage repair factors and for damage resolution, thus negatively influencing the sensitivity of cancer cells to chemo- and radiation therapies. Validation of JARID1B as a substrate …
it, de, cn
(code pays fourni par la source)
2025
conference-paper
OpenAlex
Ruihan Zhang, Borou Yu, Jiajian Min, Yetong Xin et autres
Generative AI (GenAI) is transforming filmmaking, equipping artists with tools like text-to-image and image-to-video diffusion, neural radiance fields, avatar generation, and 3D synthesis. This paper examines the adoption of these technologies in filmmaking, analyzing workflows from recent AI-driven films to understand how …
us, pa, hk, de, gb, cn, ru
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Accès ouvert
2025
preprint
OpenAlex
Marie‐Therese Lingitz, Hannes Kühtreiber, Lisa Auer, Michael Mildner et autres
Marathon running exerts physical stress and may lead to transient immune dysregulation, increasing susceptibility to airway inflammation and exercise-induced bronchoconstriction (EIB). This study investigated systemic levels of antimicrobial peptides in athletes and their association with EIB. Serum concentrations of angiogenin, human beta-defensin …
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Accès ouvert
2025
article
OpenAlex
Angela P. Moissl, Graciela E. Delgado, Marcus Edi Kleber, Frank Ch. Mooren et autres
AIMS: The study investigated the association between self-reported physical fitness (SRPF) and mortality in 3248 participants of the Ludwigshafen Risk and Cardiovascular Health (LURIC) study with a mean follow-up of 9.9 years. METHODS AND RESULTS: Self-reported physical fitness was inquired using an …
de, cz, at
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Accès ouvert
2025
conference-abstract
OpenAlex
Arne Reinecke, Andreas Haensler, Markus Weiler, Hannes Leistert et autres
Short-term flood and inundation forecasts are challenging due to the short lead time of convective heavy rainfall events and the associated uncertainties of input data or model initial conditions. These uncertainties propagate along the forecast chain to uncertainties of the prediction of …
de
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Accès ouvert
2025
article
OpenAlex
Paloma C. Frautschi, Ajay Paul Singh, Nicholas A. Stowe, Sean M. Grady et autres
ABSTRACT BACKGROUND AND PURPOSE: There is surging interest in the therapeutic potential of psychedelic compounds like psilocybin in the treatment of psychiatric illnesses like major depressive disorder (MDD). Recent studies point to the rapid antidepressant effect of psilocybin; however, the biological mechanisms …
us, nl, de
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Accès ouvert
2025
article
OpenAlex
Anna Babin-Ebell Gonçalves, Yifang Mao, Tinja Baljkas, Felix Wiedmann et autres
Liver sinusoidal endothelial cells (LSECs) critically regulate homeostatic liver function and liver pathogenesis. However, the isolation of LSECs remains a major technological bottleneck in studying molecular mechanisms governing LSEC functions. Current techniques to isolate LSECs, relying on perfusion-dependent liver digestion, are cumbersome …
de, us
(code pays fourni par la source)
2024
article
OpenAlex
Clara Daschner, Marcus Edi Kleber, Niklas Ayasse, Ksenija Stach et autres
BACKGROUND: Arterial hypertension is a significant risk factor for cardiovascular (CV) morbidity and mortality. Although central blood pressure (BP) evaluation is considered the gold standard, the reliability of non-invasive measurements remains unclear. Therefore, we compared the predictive value of invasively measured central …
de, at
(code pays fourni par la source)