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2026
article
OpenAlex
Rachel Hirschey, Jingle Xu, Alison T. Brenner, Stephanie B. Wheeler et autres
Colorectal cancer (CRC) incidence is rising among young adults, highlighting the need for targeted education and prevention. Community-informed approaches are often more effective and sustainable than traditional top-down health education models because they integrate community knowledge and lived experience from the outset. …
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2026
article
OpenAlex
Jennifer N. Hoppe, Jocelyn Lee, Tomi Akinyemiju, Danielle S. Bitterman et autres
Adequately powered analyses in precision oncology often require combining cohorts across institutions. Yet integration is constrained by the least granular source and may become infeasible when data elements are too heterogeneous to harmonize and map to a common data model. This challenge …
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2026
article
OpenAlex
Nadine Tung, Fengmin Zhao, Angela DeMichele, Olga Martínez‐Sáez et autres
PURPOSE: EA1181 (ClinicalTrials.gov identifier: NCT04266249) is a single-arm trial evaluating neoadjuvant taxane, trastuzumab, and pertuzumab (THP) in patients with clinical stage II/IIIa human epidermal growth factor receptor 2 (HER2)-positive breast cancer. This report focuses on the secondary end points of pathologic complete …
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Accès ouvert
2026
article
OpenAlex
R. Alieldin, M. Mohamed, Chin‐Shang Li, Michelle C. Janelsins et autres
PURPOSE: Cancer-related cognitive impairment is common in patients receiving cancer treatment but may be under detected by clinician-graded adverse events (AEs) alone. Patient-reported outcomes and cognitive screening may improve identification of cognitive symptoms. METHODS: We conducted a secondary analysis of the nationwide, …
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Accès ouvert
2026
article
OpenAlex
Rodney J. Ellis, Stephanie L. Pugh, James B. Yu, Felix Y. Feng et autres
Importance: The treatment of prostate cancer with radiotherapy is evolving. How quickly radiotherapy can be delivered, and the relative risks and benefits of such a treatment, is of significant public interest. Objective: To determine whether stereotactic body radiotherapy (SBRT) was superior to …
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2026
article
OpenAlex
Mutlay Sayan, Huei-Chung Huang, Erin L. Stewart, Timothy N. Showalter et autres
Background/Objectives: This study explored whether a multimodal artificial intelligence (MMAI) model integrating digitized histopathology and clinical features can identify prostate cancer patients who may benefit from neoadjuvant hormonal therapy (NHT) and whole-pelvic radiotherapy (WPRT). Methods: This secondary analysis of NRG/RTOG 9413 included …
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Accès ouvert
2026
article
OpenAlex
Sean Li, Zachary L. McCormick, Denise Lester, Michael J. DePalma et autres
Background Percutaneous 60-day peripheral nerve stimulation (PNS) of the lumbar medial branches is a minimally invasive treatment option for chronic low back pain (CLBP). A recent randomized controlled trial (RESET Clinical Trial) met its primary endpoint, with a significantly greater proportion of …
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2026
conference-abstract
OpenAlex
Hongying Sun, R. Alieldin, AnnaLynn Williams, Allison Magnuson et autres
e24094 Background: Inflammation is linked with cancer outcomes; systemic cytokine levels are associated with cognitive and functional impairments during chemotherapy. Epigenetic changes, such as DNA methylation, are also associated with cytokine levels, yet the relationship between epigenetic changes and inflammation during breast …
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2026
conference-abstract
OpenAlex
Krishna S. Gunturu, Joseph M. Unger, Dawn L. Hershman, Amy Kristine Darke et autres
2640 Background: Based on clinical trials, the expected rate of ≥ grade 3 iRAEs is ~15% for single agent ICIs and ~30-50% for ipilumimab (ipi) plus nivolumab (nivo). Predictors of irAEs remain poorly defined, limiting clinicians’ ability to anticipate and manage irAEs …
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2026
conference-abstract
OpenAlex
Jonas M. Ndeke, Kevin Spath, Lindsey Jean Mattick, Song Yao et autres
12149 Background: Chemotherapy-related cognitive impairment (CRCI) affects up to 70% of breast cancer survivors, yet recovery varies. Telomere length (TL), a marker of biological aging, may reflect biological resilience to CRCI. We evaluated whether baseline TL predicts longitudinal cognitive recovery following chemotherapy. …
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Accès ouvert
2026
article
OpenAlex
Karim Saab, Umang Gada, Michael B. Sohn, Lauren Major et autres
INTRODUCTION/AIMS: Chemotherapy-induced peripheral neuropathy (CIPN) affects 30%-60% of patients who receive neurotoxic chemotherapy. Multiple studies have shown that these symptoms negatively impact patients' quality of life. This study seeks to examine the association of the severity of pain in CIPN and different …
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Accès ouvert
2026
article
OpenAlex
Lindsey J. Mattick, Po-Ju Lin, Francisco Cartujano‐Barrera, Deborah J. Ossip et autres
Purpose To evaluate the associations of obesity and cancer-related fatigue (CRF) among breast cancer survivors, and the impact of their co-occurrence on physical function.Methods In a nationwide randomized clinical trial, we assessed body mass index (BMI; kg/m2), CRF via the Brief Fatigue …
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