Accès ouvert
2026
conference-abstract
OpenAlex
Vanessa Ota, Joice Rosa, Monna Maria Gonçalves Santa Rosa de Andrade, Adrielle Martins et autres
Background Psychiatric disorders are a leading cause of disability worldwide, arising from a complex interplay between genetic vulnerability and environmental stressors. Parental mental disorders (PMD) significantly increase offspring risk through both genetic transmission and the shaping of the child's social environment. This …
br
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Kathryn Freeman, Katie Scott, Alyson Zwicker, Janice Fullerton et autres
Background Polygenic scores (PGS) for psychiatric traits are associated with the onset of severe mental illness (SMI) among youth of European ancestry; however, the replicability of these associations in ethnically diverse populations remains unclear. This study examined whether associations between PGS and …
ca, au, gb, nl, br, es, us
(code pays fourni par la source)
Accès ouvert
2026
conference-abstract
OpenAlex
Liriel Almodobar, Lucas Toshio Ito, Adrielle Martins, Marcos Santoro et autres
Background Psychiatric disorders are highly comorbid and share genetic liability, suggesting that latent dimensions may better capture their biology. The Psychiatric Genomics Consortium Cross-Disorder (CD) group identified latent genetic factors across psychiatric disorders (Grotzinger et al.2026) while in the Brazilian High-Risk Cohort …
br
(code pays fourni par la source)