Panax notoginseng saponins ameliorates glucolipid metabolism disorders and hepatic injury in T2DM mice via gut microbiota modulation
Tianxin Zhu, Jie Tao, Biyuan Yang, Zhenjie Wu et autres
Background Despite low oral bioavailability, Panax notoginseng saponins (PNS) exert anti-diabetic effects, possibly through gut microbiota-mediated indirect mechanisms. Aim This study investigated whether PNS regulate glucolipid metabolism in T2DM by modulating gut microbiota and activating the FXR/SHP pathway via its metabolite PPT. …
cn (code pays fourni par la source)
0 citations
Journal of Ginseng Research