Multi-ancestry polygenic risk scores for the prediction of type 2 diabetes and complications in diverse ancestries
Alicia Huerta‐Chagoya, Joohyun Kim, Ravi Mandla, Yingchang Lu et autres
Background: Polygenic risk scores (PRSs) improve prediction of the development of type 2 diabetes over the use of clinical risk factors alone; however, they perform poorly in populations of non-European ancestry, limiting their global clinical utility. We aimed to deliver comprehensive and …
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