A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers
J Coignard, M Lush, J Beesley, TA O'Mara et autres
Abstract Breast cancer (BC) risk for BRCA1 and BRCA2 mutation carriers varies by genetic and familial factors. About 50 common variants have been shown to modify BC risk for mutation carriers. All but three, were identified in general population studies. Other mutation …
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