Does acute pyelonephritis skew outcomes in registrational trials of novel antibiotics for complicated urinary tract infections? A systematic review and meta-analysis
Giovanni Mori, Tommaso Ceccato, Simone Botti, Simone Giuliano et autres
BACKGROUND: Acute pyelonephritis (AP) and complicated urinary tract infections (cUTIs) are pooled in registrational RCTs of new antibiotics. We assessed whether outcomes differ between subtypes and which component of the composite endpoint drives any difference. METHODS: Across ten registrational RCTs we estimated …
it, no, dk (code pays fourni par la source)
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Clinical Infectious Diseases