Gut microbiota and uric acid excretion signaling in pathogenesis of hyperuricemia and acute gouty arthritis
Meiling Wang, Ruifang Yang, Honglin An, Bingyan Chen et autres
Hyperuricemia (HUA) and acute gouty arthritis (AGA) represent distinct pathological stages of gout, with the intestine playing a critical role in uric acid (UA) excretion. By establishing HUA and AGA mouse models, we observed both induced renal and intestinal pathology, elevated inflammatory …
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