Genetic architecture of cytokine autoantibodies and associated risk of common diseases
Jakob Hjorth von Stemann, Joseph Dowsett, Rebecca Svanberg Teglgaard, Maria Didriksen et autres
Anti-cytokine autoantibodies are increasingly recognized as modulators of immune function and determinants of disease risk, yet their genetic basis and population-level impact remain unclear. Here we perform genome-wide association studies of autoantibodies against IL-1α, IL-6, IL-10, IFN-α, IFN-β, IFN-γ and GM-CSF in …
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