Metastasis of triple negative breast cancer is regulated by a targetable miR-342-E2F network
Victoria Kiriaki Arnet, Cameron N. Johnstone, Richard P. Redvers, Caroline A. Chambers et autres
Triple-negative breast cancer (TNBC) has a high incidence of metastasis and limited therapeutic options. Here, we identify a multimodal and targetable miR-342-E2F network that regulates metastatic outgrowth in TNBC. Through integrating clinical and experimental datasets, we uncover miR-342 as a suppressor of …
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EMBO Molecular Medicine