High tPA activity but absent PAI-1 and plasminogen function early in intrapleural lytic therapy
Elizabeth R Maginot, Peter K. Moore, Cesar Davila-Chapa, Jiashan Wang et autres
To the Editor Intrapleural fibrinolytic therapy (IPFT) for complicated parapneumonic effusions and empyema (CPE/E) is inefficient resulting in average hospital lengths of stay of 14 days and costs the U.S. healthcare system more than 1 billion dollars annually.1 The current dogma is …
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American Journal of Respiratory and Critical Care Medicine