Pan-African hybridization of PfSPZ increases antigenic diversity and replicative capacity for malaria vaccine design
Lucia Pazzagli, Bethany Jenkins, Ankit Dwivedi, Asha Patil et autres
Plasmodium falciparum sporozoite (PfSPZ) vaccines, comprised of aseptic, purified, live parasites that arrest during or just after liver stage development, show excellent safety and efficacy in humans. They can induce complete protection against Pf infection, mediated primarily by cellular immune responses against …
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