In situ Discovery of Immune Repertoire Reveals Antitumor Immunity and Therapeutic Antibodies
Haorui Zhang, Peiyu Wang, Yahui Zhao, Lukai Yang et autres
ABSTRACT Spatial transcriptomics offers a glimpse into the immunology of tissues. However, limitations in spatial transcriptomics preclude the detection of highly diverse, low-abundance, and previously unknown sequences, including immune repertoires and microbiota. Here, we introduce Archimap, a spatial transcriptomic platform that simultaneously …
cn (code pays fourni par la source)
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bioRxiv (Cold Spring Harbor Laboratory)