GCH1 genetic variation as a prognostic factor in Parkinson’s disease across populations
Jung Hwan Shin, María Teresa Periñán, Joo Won Jang, Laurel Screven et autres
Abstract Background Pathogenic variants in GCH1 have been associated with Parkinson’s disease (PD), but the clinical phenotype and longitudinal disease course of GCH1 -associated PD remain incompletely characterized. Objectives To characterize the genetic spectrum, clinical phenotype, and longitudinal progression of GCH1 -associated …
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