Unlocking extracellular vesicle-mediated efficient DNA delivery for long-lasting transgene expression
Melissa Tan, Yumi Kawamura, Carol Wang, Ryan Schneider et autres
Achieving efficient DNA delivery for sustained transgene expression while minimizing immune response remains a significant challenge in gene therapy. Here, we conduct an in-depth characterization of red blood cell-derived extracellular vesicles (RBCEVs) and evaluate their potential as DNA delivery vehicles targeting specific …
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Molecular Therapy