Tenfold Expansion Submicrometer MALDI Mass Spectrometry Imaging of Tissues and Cultured Cells
Chengyi Xie, Jianing Wang, Lei Guo, Xin Diao et autres
Achieving submicrometer lateral resolution in matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) is essential for molecular characterization at the single-cell and subcellular levels but is fundamentally limited by optical focusing and matrix crystallization. Here, we present tenfold expansion mass spectrometry imaging (10X …
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Angewandte Chemie International Edition