Empirical treatment with valganciclovir in infants living with HIV and hospitalised with severe pneumonia in Africa: a multicentre, open-label, factorial, randomised, controlled, superiority trial
Cinta Moraleda, Alfredo Tagarro, Sara Domínguez‐Rodríguez, Victor Musiime et autres
BACKGROUND: Mortality among infants with severe HIV-associated pneumonia remains high. This trial (EMPIRICAL) tested whether empirical valganciclovir treatment for cytomegalovirus improves survival in infants in Africa. METHODS: This multicentre, open-label, group-sequential designed, 2 × 2 factorial, randomised, controlled, superiority trial was conducted …
es, Ouganda, Zimbabwe, Zambie, Malawi, gb, Mozambique, Côte d’Ivoire, fr, nl, it, cu (code pays fourni par la source)
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The Lancet