Accès ouvert
2026
article
OpenAlex
Mutsa Bwakura-Dangarembizi, Elizabeth Chappell, Cissy Kityo, Diana Louis Anena et autres
BACKGROUND: Adolescents living with HIV have poorer treatment outcomes than other age groups and might benefit from long-acting-injectable (LAI) antiretroviral therapy (ART). We evaluated efficacy and safety of LAI cabotegravir-rilpivirine compared with daily oral ART in adolescents living with HIV with virological …
Zimbabwe, gb, Ouganda, Kenya, Afrique du Sud, it, nl
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Julia Anna Bielicki, Michelle Clements, Victor Musiime, David Paul Moore et autres
BACKGROUND: WHO recommends 5 days of intravenous antibiotics for children hospitalised with severe community-acquired pneumonia (CAP). We aimed to investigate the safety of a step-down to different oral antibiotics and the shortest effective duration. METHODS: PediCAP was an open-label, parallel group, 2 …
gb, Ouganda, Afrique du Sud, Mozambique, Zambie, Zimbabwe, it
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Cinta Moraleda, Alfredo Tagarro, Sara Domínguez‐Rodríguez, Victor Musiime et autres
BACKGROUND: Mortality among infants with severe HIV-associated pneumonia remains high. This trial (EMPIRICAL) tested whether empirical valganciclovir treatment for cytomegalovirus improves survival in infants in Africa. METHODS: This multicentre, open-label, group-sequential designed, 2 × 2 factorial, randomised, controlled, superiority trial was conducted …
es, Ouganda, Zimbabwe, Zambie, Malawi, gb, Mozambique, Côte d’Ivoire, fr, nl, it, cu
(code pays fourni par la source)