VSIG3 preserves mitochondrial homeostasis and restrains CD4⁺ T-Cell infiltration in myocardial ischemia–reperfusion injury through regulation of mitochondrial-derived vesicles
Jian Hou, Liqun Shang, Zi Yan, Yuanhan Ao et autres
Myocardial ischemia-reperfusion (MI/R) injury remains an inevitable and severe clinical challenge during cardiac surgery, primarily characterized by mitochondrial dysfunction and robust CD4 + T cell infiltration. In this study, we investigated the therapeutic potential of the immune checkpoint molecule VSIG3 (V-set and …
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Journal of Nanobiotechnology