Genome-wide association study of untargeted plasma metabolomic profiles identifies host genetic regulation in people with HIV
Mariam Ait Oumelloul, Adriaan van der Graaf, Simon Tang, Christian W. Thorball et autres
People with human immunodeficiency virus (PWH) exhibit accelerated aging and a higher prevalence of aging-related conditions, despite effective antiretroviral therapy. The biological mechanisms involved remain incompletely understood. Integrating genomic and metabolomic profiling may help uncover genes and pathways contributing to aging-related disease …
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