Modeling cancer with bacteria-integrated tumor microenvironments using biomaterials: Emerging concepts and opportunities
Keuna Jeon, Uijin Kim, Chang-Hun Ji, Meenakshi Kamaraj et autres
The tumor microenvironment (TME) is a dynamic and heterogeneous ecosystem in which cancer, stromal, immune, and physicochemical components collectively regulate disease progression and therapeutic response. Recent evidence further indicates that intratumoral bacteria are active contributors to tumor metabolism, immune modulation, and treatment …
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