Interplay between CARD9 genetic variants and fungal colonization patterns among patients with diabetes
Aiah M. Khateb, Rahaf Ghazi Alharbi, Lujain Alsweed, Mohammed Doud et autres
Background Diabetes mellitus significantly increases susceptibility to opportunistic fungal colonization; however, the genetic architecture underlying this vulnerability in Middle Eastern populations remains underexplored. Caspase recruitment domain-containing protein 9 (CARD9) is a fundamental adaptor in fungal sensing. While CARD9 deficiency is traditionally viewed …
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Frontiers in Fungal Biology