Kidney Transplantation in Two Highly Sensitized Candidates after CAR T-Cell Therapy
Vijay Bhoj, Mary Kaminski, Huiwu Zhao, Kyle Jackson et autres
HLA sensitization poses a major challenge to kidney transplantation for patients with end-stage kidney disease, especially for highly sensitized candidates. Attempts at antibody elimination (desensitization) have had inconsistent efficacy and have often failed to produce sustained reductions in anti-HLA antibodies in patients …
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7 citations
New England Journal of Medicine