Iron-deficiency in the tumor microenvironment reprograms tumor-immune interactions in a sex biased manner
Swetapadma Sahu, Yue Hao, Angela Baker, Kondaiah Palsa et autres
Abstract Background Glioblastoma (GBM) is a sex-biased disease characterized by higher incidence and poorer survival in males. These sex differences are primarily driven by metabolic and immune signatures, with iron metabolism playing a major role. While iron is essential for tumor cell …
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bioRxiv (Cold Spring Harbor Laboratory)