Large-scale genome- and phenome-wide analyses reveal the genetic architecture, pathophysiology and comorbidity of restless legs syndrome
Xiaoxi Jing, Zi Wang, Jacob Williams, Junpeng Zhao et autres
Abstract Restless legs syndrome (RLS) is a common sleep-related movement disorder, affecting approximately 4% of adults worldwide, with a substantially higher prevalence in individuals of European ancestry, reaching 5-13%. However, its genetic architecture and pathophysiology remain poorly understood. Here, we conducted a …
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