Regulatory mechanisms of LGR4 on cancer and cancer stem cell properties
Jialei Yang, Jinye Zhao, Houchang Liu, Saili Luo et autres
Leucine-rich repeats containing G protein-coupled receptor 4 (LGR4) is a receptor belonging to the G-protein-coupled receptor superfamily. LGR4 can be activated by ligands such as R-spondins (RSPOs), Norrin, and the ligand of the receptor activator of nuclear factor kappa-B(RANKL) to regulate signaling …
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