Accès ouvert
2026
preprint
OpenAlex
Lauryn E. Bailey, Sam C Wolff, Tarek Zikry, Garrett A. Sessions et autres
Dedifferentiated liposarcoma is a rare mesenchymal malignancy driven by amplification of chromosome 12q13-15, which includes the oncogenes CDK4 and MDM2. CDK4 amplification provides a rationale for targeted therapy with CDK4/6 inhibitors, and abemaciclib has shown the most durable activity reported to date …
us
(code pays fourni par la source)
Accès ouvert
2026
dataset
OpenAlex
Lauryn E. Bailey, Sam Wolff, Tarek Zikry, Garrett Sessions et autres
Single-cell datasets for Non-Genetic Mechanisms of Fractional Resistance to Abemaciclib in Dedifferentiated Liposarcoma. DDLPS_cell_line_Lipo246_subsampled_data.h5ad: Subsampled dataset of the dedifferentiated liposarcoma (DDLPS) cell line LPS246 across three treatment conditions (control, 50 nM, and 250 nM abemaciclib), 2,000 cells per condition (6,000 cells total). …
us
(code pays fourni par la source)
Accès ouvert
2026
dataset
OpenAlex
Lauryn E. Bailey, Sam Wolff, Tarek Zikry, Garrett Sessions et autres
Single-cell datasets for Non-Genetic Mechanisms of Fractional Resistance to Abemaciclib in Dedifferentiated Liposarcoma. DDLPS_cell_line_Lipo246_subsampled_data.h5ad: Subsampled dataset of the dedifferentiated liposarcoma (DDLPS) cell line LPS246 across three treatment conditions (control, 50 nM, and 250 nM abemaciclib), 2,000 cells per condition (6,000 cells total). …
us
(code pays fourni par la source)