Magnetic resonance imaging-based simplified MaRIA scores are associated with future surgery in Crohn’s disease, but modest correlation with ileo-colonoscopic inflammation limits their utility in clinical trials: results from the PROFILE trial
Megha Bhandari, Mohmmed Tauseef Sharip, Nurulamin M Noor, Samir Khwaja et autres
BACKGROUND: Ileo-colonoscopy provides accurate assessment of mucosal inflammation in Crohn's disease. Magnetic resonance imaging (MRI) offers a non-invasive alternative. MRI-based scores such as the simplified MaRIA (sMaRIA) have been proposed for measuring treatment response in clinical trials, but systematic comparisons with endoscopic …
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2 citations
Journal of Crohn s and Colitis