Can Gülersönmez

LDL RECEPTOR-MEDIATED UPTAKE OF LIPOPROTEINS FUELS HUMAN CD4+ T CELL POLARIZATION TOWARDS A C-MAF-IL-10 AND FOXP3-DRIVEN REGULATORY PHENOTYPE

Angela Markovska, Niels Van Heusden, Enric Mocholí, Edwin Stigter et autres

LDL receptor–mediated lipoprotein uptake fuels human CD4+ T cell polarization toward a c-MAF/IL-10– and FOXP3-driven phenotype

Angela Markovska, Niels S. van Heusden, Dagmar Duijzer, Alejandra Bodelón et autres

Human CD4+ T cells utilize nutrients, including lipids, to support their activation and polarization. Considering the pivotal role of lipoproteins in lipid transport, we reasoned that lipoprotein uptake and processing could effect CD4+ T cell function. Here, we demonstrate that activation of …

nl, es (code pays fourni par la source)

Hydrogen Peroxide induces resistance to DNA damage in a localization and p53 dependent manner

Janneke P. Keijer, Paulien E. Polderman, Paula Alcaraz-Sobrevals, Robert M. van Es et autres

Abstract Organisms need to be able to adapt to a changing environment in order to survive. The adaptive response invoked by a low dose of a stressor resulting in resistance to high levels of that stressor is known as hormesis and can …

nl (code pays fourni par la source)