Prognostic stratification by LGR5 expression identifies surface-accessible, structurally ligandable and condensate-forming targets in colorectal cancer
Lucía Paniagua‐Herranz, Alejandro Feito, Cristian Privat, Luis Álvarez-Carrión et autres
Abstract Background LGR5 marks colorectal cancer stem cells and is associated with poor outcome, but its expression on normal intestinal stem cells has constrained direct therapeutic targeting, and the molecular landscape of LGR5-high tumors remains incompletely defined. A transcriptional signature is not …
es, gb, hu (code pays fourni par la source)