Pedro Augusto Alves

Autoantibodies neutralizing type I interferons underlie a third of cases of Chikungunya virus encephalitis or myelitis

Vu L. Tran, Adrian Gervais, Marie-Mechtilde Champeaux, Maria Paula de Souza Sampaio et autres

Abstract Chikungunya virus (CHIKV) infection is typically not life-threatening but may, in rare cases, affect the central nervous system (CNS). In three cohorts of confirmed CHIKV cases from Martinique (French overseas territory) and Brazil (patients aged 0–89 years, n = 245), 20 …

us, fr, ca, br, mq, vn (code pays fourni par la source)

Assessment of a recombinant influenza virus carrying interleukin 7 gene as a platform for novel immunotherapeutic approaches

Sarah Giarola da Silva Messias, Ianca Évelin Silva de Paula, Kimberly Freitas Cardoso, Cristiana Couto Garcia et autres

Influenza virus remains a major global public health threat due to its high transmissibility, ability to cause severe disease, and pandemic potential. Although vaccination is the main strategy for reducing the burden of influenza, it has notable limitations. Therefore, novel therapeutic and …

br, us (code pays fourni par la source)

Genomic epidemiology of dengue virus serotype 3 lineage 3III_B.3.2 in Brazil: insights into its spread and dengue severity amid co-circulation of multiple dengue serotypes

Caroline do Nascimento Ferreira, Carla Adriane Royer, Camila Confortin, Nélson Marques et autres

Background: After over a decade of minimal circulation, DENV-3 reemerged in Brazil in 2023, driven by the newly detected lineage 3III_B.3.2. Elucidating the patterns of DENV-3 spread and impact on public health, is critically important in the context of Brazil's hyperendemic dengue …

br, de (code pays fourni par la source)

Assessment of a recombinant influenza virus carrying interleukin 7 gene as a platform for novel immunotherapeutic approaches

Sarah Giarola da Silva Messias, Ianca Évelin Silva de Paula, Kimberly Freitas Cardoso, Cristiana Couto Garcia et autres

Long-Term Immunogenicity, Safety, and Reactogenicity of CoronaVac and Heterologous Booster Vaccines: A Two-Year Cohort Study in Brazil

Sarah Contin VM, Nathalie Almeida BF, Priscilla Filgueiras S, Camila Corsini A et autres

During the covid-19 pandemic, CoronaVac (Sinovac/Instituto Butantan) was one of the pioneering vaccines used in Brazil and worldwide. This study evaluated the immunogenicity, safety and reactogenicity over two years in 1.675 participants in Belo Horizonte, Minas Gerais, Brazil who received CoronaVac as …

br (code pays fourni par la source)