Serine Stabilizes SLC7A11 and Enhances Cystine Influx to Protect Against Acute Pancreatitis
Yan Huang, FU Fei, Lingli Deng, Yiqin Wang et autres
SUMMARY Lethal sterile inflammatory diseases are linked to amino acid metabolism, but the role of serine remains unclear. Here, we show that dysregulated serine metabolism and reduced plasma serine levels correlate with disease severity of acute pancreatitis (AP) in patients and mouse …
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bioRxiv (Cold Spring Harbor Laboratory)